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Fold increase in the expression of HCAD Calu-6 anaplastic epithelial lung carcinoma cells. Cells were treated with either 1 mM aminoguanidine (AG), 5 μM PN11144, 5 μM 2d or 10 μM of the indicated test compound for 24 or 48 hours. Each data point is the average of three determinations that in no case differed by more than 5%.
