Skip to main content
. Author manuscript; available in PMC: 2013 Apr 6.
Published in final edited form as: J Chromatogr A. 2012 Jan 9;1232:266–275. doi: 10.1016/j.chroma.2011.12.100

Fig. 1.

Fig. 1

Schematic illustration of isotopic N-dimethyl labeling for relative quantitation of protein nitration. Reductive N-dimethylation of aliphatic amines in a peptide is carried out by using H12CHO or D13CDO and sodium cyanoborohydride. The isotopic mass shift between the light and heavy labeled peptides is Δ = 6 Da.