Table 1.
General characteristics of H1N1 vaccine recipients and controls
| Unvaccinated (n = 12) | Vaccinated (n = 81) | Responders (n = 36) | Non-responders (n = 44) | |
|---|---|---|---|---|
|
aCD4+ T cells/μL Mean ± SD |
420 ± 235 |
529 ± 269 |
609 ± 277 |
475 ± 241 |
| 0–200 |
1 (8.3%) |
9 (11%) |
3 (8.3%) |
5 (11%) |
| 201–350 |
5 (42%) |
13 (16%) |
4 (11%) |
9 (20%) |
| 351–500 |
2 (17%) |
15 (19%) |
4 (11%) |
11 (25%) |
| >500 |
4 (33%) |
44 (54%) |
25 (69%) |
19 (43%) |
| Log10 viral load Median (IQR) |
1.60 (1.60-2.09) |
1.60 (1.60-2.70) |
1.60 (1.60-2.34) |
1.60 (1.60-3.07) |
| ≤1.60 |
8 (67%) |
50 (62%) |
23 (64%) |
27 (61%) |
| 1.61-2.60 |
3 (25%) |
11 (14%) |
7 (19%) |
4 (9.1%) |
| 2.61-3.00 |
0 |
2 (2.5%) |
1 (2.8%) |
1 (2.3%) |
| 3.01-4.00 |
0 |
6 (7.4%) |
1 (2.8%) |
5 (11%) |
| >4.00 |
1 (8.3%) |
12 (14%) |
4 (11%) |
7 (16%) |
| Age (years) Mean ± SD |
45.7 ± 6.6 |
45.2 ± 7.2 |
44.2 ± 7.5 |
46.2 ± 7.0 |
| Male |
8 (67%) |
56 (69%) |
27 (75%) |
29 (66%) |
| Female |
4 (33%) |
25 (31%) |
9 (25%) |
16 (36%) |
| bPre-existing anti-H1N1 | ND | 28 (35%) | 22 (61%) | 6 (14%) |
aNumber of CD4+ T cells/μL peripheral blood at time nearest to, but before H1N1 vaccination.
bNumber of individuals in each group with antibodies against H1N1 HA before vaccination.