Table 2.
Accuracy of genotyping approaches at correctly predicting coreceptor tropism
| Method | CXCR4-using accuracy | CXCR4-exclusive accuracy | R5X4 accuracy |
|---|---|---|---|
| PSSM_sinsi |
88 |
88 |
88 |
| PSSM_X4R5 |
86 |
87 |
86 |
| C-PSSM |
91 |
90 |
91 |
| Geno2Pheno_FPR5 |
94 |
93 |
94 |
| Geno2Pheno_FPR10 |
92 |
91 |
92 |
| Geno2Pheno_FPR20 |
88 |
87 |
90 |
| WetCat_C4.5 |
70 |
70 |
70 |
| WetCat_C4.5 pos. 8&12 |
70 |
70 |
70 |
| WetCat_PART |
77 |
76 |
79 |
| WetCat_SVM |
81 |
82 |
81 |
| 11/24/25 |
81 |
81 |
82 |
| 11/25 |
79 |
76 |
82 |
| Raymond | 86 | 88 | 85 |
Accuracy scores are presented for a combined dataset containing CXCR4-using viruses (both CXCR4-exclusive and dual-tropic viruses) as well as separately for the CXCR4-exclusive and dual-tropic viral sequences.