Table 4.

Results of meta-analysis comparing outcomes in laparoscopic and open distal pancreatectomy in high-quality studies

Outcome of interest	Studies, n	Patients, n	OR/WMD	95% CI	P-value*
Operative outcomes
Operation time, min	5	343	19.71	−10.01 to 49.44	0.19
Intraoperative blood loss, ml	5	343	−263.36	−330.48 to −196.23	<0.00001
Blood transfused	5	375	0.28	0.11–0.76	0.01
Splenic preservation	10	1148	2.98	2.18–4.06	<0.00001
Postoperative recovery
Time to oral intake, days	2	161	−2.63	−4.23 to −1.03	0.001
Time to first flatus, days	2	161	−1.80	−2.14 to −1.47	<0.00001
Hospital stay, days	5	343	−4.98	−7.04 to −2.92	<0.00001
Postoperative complications
Clinically significant fistula	4	335	0.67	0.41–1.09	0.11
Postoperative haemorrhage	4	329	1.87	0.59–5.95	0.29
Intra-abdominal abscess	6	331	0.78	0.25–2.45	0.67
Intra-abdominal fluid collections	3	304	1.47	0.67–3.22	0.34
Surgical site infection	5	264	0.37	0.18–0.75	0.006
Mortality	11	1155	0.61	0.16–2.27	0.46
Reoperation	8	683	0.90	0.43–1.84	0.76
Readmission	5	772	0.70	0.41–1.21	0.20

WMD, weighted mean difference; OR, odds ratio; 95% CI, 95% confidence interval.