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. 2012 Nov;23(11):1835–1846. doi: 10.1681/ASN.2012010022

Figure 1.

Figure 1.

PAM staining and Masson’s trichrome staining of kidney sections. (A) Representative glomeruli of PAM-stained kidneys from control, DM, and DM+T0901317 mice. Glomerular hypertrophy and mesangial matrix expansion are evident in the DM group. Original magnification, ×400. (B) MMI in glomeruli. T0901317 suppresses the increase in the MMI compared with the DM group. Data are means ± SEM. *P<0.001. (C) Representative photomicrographs of kidney sections with Masson’s trichrome staining. Interstitial fibrosis is significantly increased in the DM group compared with the control group and significantly decreased in the DM+T0901317 group compared with the DM group. Original magnification, ×400. (D) Percentages of fibrosis in glomeruli. Data are means ± SEM. #P<0.001, *P<0.05.