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. 2012 Nov;23(11):1835–1846. doi: 10.1681/ASN.2012010022

Figure 7.

Figure 7.

LXR agonist inhibits AP-1 binding to the proximal OPN promoter. mProx24 cells were pretreated for 24 h with vehicle (DMSO) or 1 or 5 μmol/L T0901317 and stimulated with HG medium (25 mM) for 24 h. ChIP assays were performed using anti–c-Fos and anti–phospho-c-Jun antibodies. Total extract (input) and rabbit IgG were used as controls. The ethidium bromide-stained agarose gels shown are representative of three independently performed experiments.