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. Author manuscript; available in PMC: 2013 Apr 25.
Published in final edited form as: Nature. 2012 Sep 19;490(7421):502–507. doi: 10.1038/nature11531

Figure 3. Batf compensates for CD8α+ cDC development in Batf3−/− mice.

Figure 3

a, Wild type (WT), or Batf3−/− (BATF3KO) BM cells were infected with GFP-RV33 (Empty) or retrovirus expressing the indicated cDNA and cultured with Flt3L7. Histograms for the indicated markers are for B220CD11c+ cells on day 10. Numbers are the percent of cells in the gate. b, Inguinal lymph nodes from WT, Batf3−/− (BATF3 KO) or Batf−/−Batf3−/− mice (BATF1/3 DKO) on 129SvEv or C57BL/6 backgrounds were analyzed by FACS. Shown are histograms for DEC205 and CD8α. c, CD4 T cells of the indicated genotype were differentiated twice under TH2 conditions5 and analyzed by FACS for intracellular IL-10.

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