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. Author manuscript; available in PMC: 2013 Apr 25.
Published in final edited form as: Nature. 2012 Sep 19;490(7421):502–507. doi: 10.1038/nature11531

Figure 4. Batf2 compensates for Batf3 in CD8α+ and CD103+ cDC development during T. gondii infection.

Figure 4

a, Wild-type (WT) and Batf2−/− (BATF2KO) mice were infected with T. gondii and monitored for survival. n=29 for WT (dashed line) and Batf2−/− (solid line) mice. b, Shown are percentages of lung CD103+ DCs of total CD45.2+ cells for uninfected and infected (T. gondii) mice on day 10. n=5 from one of three experiments. c, WT or Batf3−/− (BATF3KO) BM cells were infected with the indicated retrovirus, cultured with Flt3L and analyzed by FACS on day 10. d, Groups of 5 mice each of the indicated genotypes were treated with vehicle (PBS) or IL-12 (IL12) and analyzed by FACS after 3 days. Shown are percentages of CD8α+ cDCs as a total of splenic cDCs.