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Diagnostic Accuracy of Elevated ALT for AAT Liver Disease
| Lab Defined Normal ALT | Strict Normal ALT | |
|---|---|---|
| Sensitivity | 11.9% | 52.4% |
| Specificity | 92.4% | 51.0% |
| PPV | 10% | 7.0% |
| NPV | 92.3% | 93.8% |
| LR+ | 1.57 | 1.07 |
| LR− | 0.95 | 0.93 |
PPV, positive predictive value; NPV, negative predictive value; LR+, likehood ratio positive, LR −, Likehood ratio negative
