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2.5 Å resolution crystal structure of compound 21a bound to Aurora-A (PDB code 4B0G). The color scheme used is nitrogen, blue; oxygen, red; bromine, brown; carbon in Aurora-A, white; carbon in 21a, green. The final 2mFo-DFc electron density map surrounding 21a is shown as a gray wire-mesh, contoured at 1.0 σ.
