Table 6. Kd Values for Compound 27e.
| kinase | Kd (nM) |
|---|---|
| Aurora-A | 7.5 |
| Aurora-B | 48 |
| FLT3 | 6.2 |
| FLT3(D835H) | 11 |
| FLT3(D835Y) | 14 |
| FLT3-ITD | 38 |
| FLT3(K663Q) | 5.1 |
| FLT3(N841I) | 16 |
| FLT3(R834Q) | 110 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.