FIG. 5.

MSC sizes can differ between cell lines and with cell passaging. Cell sizes were measured as described in Materials and Methods. (A) Bars represent size bins for pooled individual cells of PCBM1641 or PCBM1632 at P3, P5, and P7. (B) Average size of cells from PCBM1641 (black) and PCBM1632 (white) as a function of passage. Sample sizes were the following: PCBM1641: P3 (n=13), P5 (n=16), and P7 (n=15). PCBM1632: P3 (n=13), P5 (n=13), and P7 (n=5). Error bars represent standard error of the mean. Asterisk indicates significant difference (p<0.019) between donors at that passage, marked with a horizontal bar. Significance was also seen within both donors at P3 versus P5, P5 versus P7, and P3 versus P7 (p≤0.004), as indicated by §.