Table 3.

SNP Ratio Test (SRT) pathway analysis results

HSP family	Total # SNPs	P=0.05	P=0.01	P=0.001
HSP40	6352	0.72 (279)	0.68 (50)	0.31 (7)
DNAJA	542	0.62 (13)	0.19 (9)	0.02 (7)
DNAJB	1390	0.49 (70)	0.96 (1)	1.00 (0)
DNAJC	4420	0.67 (196)	0.56 (40)	1.00 (0)
BAG	517	0.68 (16)	0.20 (10)	0.02 (9)
CHIPlike	292	1.00 (0)	1.00 (0)	1.00 (0)
Prefoldin	912	0.10 (93)	0.03 (29)	0.11 (3)
HSP70	1880	0.78 (94)	0.34 (29)	0.37 (2)

Pathway analysis results of the different HSP families at three different cut-offs for significance (P=0.05, P=0.01 and P=0.001). The p-values given in the table depict the chance that the number of SNPs found to be significant at the given p-value cut-off is more than expected by chance. In bold are those p-values passing a nominal threshold of significance. In brackets are the number of SNPs passing the threshold of significance depicted. DNAJA, DNAJB and DNAJC are sub-families of HSP40.