Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Oct 29;7(10):e48282. doi: 10.1371/journal.pone.0048282

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2012 Tacutu et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

The worm longevity network (WLN) includes 205 previously identified LAGs (dark green) and their 666 first-order protein interaction partners (light green). The graphical output of the network was generated using Cytoscape 2.8.0 [51]. Size of nodes is proportional with the number of PPIs in the BioGRID interactome. Genes in the network are more connected and more interconnected than would be expected by chance, suggesting shared functionality. Because many genes that influence longevity function in complexes, signaling networks or in conjunction with cofactors, the 666 first-order interacting LAG partners may be enriched with previously unidentified longevity genes.