Table 1. Inflammatory gene expression in infected mouse kidneys by NanoString analysis.

Gene	p value	F C	gene	p value	F C	Gene	p value	F C
Nos2*	0.0153	54.2	Il10rb	0.0002	−2.6	Rps6ka5	0.0249	−5.1
Ccl3*	0.0000	42.1	Keap1	0.0024	−2.6	Kng1	0.0034	−5.2
Il1rn	0.0205	37.1	Hmgn1	0.0004	−2.7	Prkca	0.0019	−6.1
Fos*	0.0454	26.6	Nfe2l2	0.0003	−2.8	Il7	0.0046	−6.5
Maff	0.0000	24.2	Mknk1	0.0004	−2.8	Traf2*	0.0225	−7.2
Ccl4	0.0050	18.2	Mapkapk5	0.0031	−3.0	Mef2a	0.0292	−7.6
Il18rap	0.0002	17.9	Map3k7	0.0023	−3.0	Plcb1	0.0155	−7.6
Il1a	0.0120	15.8	Tlr3	0.0152	−3.0	Fxyd2	0.0437	−7.7
Tnf	0.0004	14.5	Map2k4	0.0022	−3.2	Nfatc3	0.0054	−8.0
Il1b	0.0096	14.1	Nr3c1	0.0196	−3.4	Ly96	0.0005	−8.6
Itgb2	0.0446	12.6	Raf1	0.0100	−3.5	Map2k6*	0.0160	−9.7
Cebpb	0.0151	9.1	Gnaq	0.0009	−3.6	Il15*	0.0260	−13.5
Il8rb	0.0413	9.0	Map3k5	0.0048	−4.1	C8a*	0.0234	−193.2
Hspb1	0.0341	8.9	C2	0.0007	−4.2
Tlr2	0.0008	6.5	Creb1	0.0217	−4.3
C3	0.0097	5.8	Lta	0.0035	−4.3
Limk1	0.0178	3.9	Mef2c	0.0122	−4.3
Cxcr4	0.0095	2.8	Tgfb2	0.0328	−4.7
Tgfb1	0.0055	2.7	Stat1	0.0011	−4.9

F C – fold change in mRNA expression in kidneys of mice 3 days after infection with A72 wild type versus the dur1,2Δ strain KWN6. * indicates selected genes validated with qRT-PCR (Figure S1).