Table 4.
Rank | Active substance, drug formulation | No of prescriptions | Potentially harmful or known to be harmful excipients |
---|---|---|---|
1 |
Gentamicin, inj solution |
200 |
Parabens, sodium metabisulphite |
2 |
Simeticone, oral suspension |
108 |
Sodium benzoate, saccharin sodium, silicium dioxide, sodium cyclamate, sorbic acid |
3 |
Heparin, inj solution |
86 |
Benzyl alcohol, parabens |
4 |
Laurilsulphate + Sorbitol + Sodium citrate, rectal solution |
60 |
Sorbic acid |
5 |
Salbutamol, nebulisation solution |
54 |
Benzalkonium chloride, propylene glycol |
6 |
Dobutamine, inj solution |
45 |
Sodium metabisulphite |
7 |
Epinephrine, inj solution |
36 |
Sodium metabisulphite |
8 |
Iron, oral solution |
32 |
Parabens, saccharin sodium |
9 |
Budesonide, nebulisation solution |
31 |
Polysorbate 80, disodiumedetate |
10 |
Chloramphenicol, opthalmic solution |
29 |
Benzalkonium chloride, polysorbate 80, borax, boric acid |
11 |
Caffeine, solution |
29 |
Sodium benzoate |
12 |
Phenobarbital, tablet |
29 |
Silicium dioxide, gelatin |
13 |
Paracetamol, suppository |
29 |
Disodium hydrogen phosphate |
14 |
Piperacillin + tazobactam, inj solution |
25 |
Disodium edetate |
15 |
Paracetamol, inj solution |
24 |
Disodium hydrogen phosphate |
16 |
Hydrocortisone, inj solution |
23 |
Benzyl alcohol, disodium hydrogen phosphate |
17 |
Epoetin beta, inj solution |
22 |
Disodium hydrogen phosphate, glycine, calcium chloride dihydrate, leucine, |
18 |
Ibuprofen, inj solution |
21 |
Trometamol |
19 |
Hyoscine butylbromide, tablet |
20 |
Silicium dioxide |
20 |
Spironolactone, tablet |
18 |
Silicium dioxide |
21 |
Zidovudine, oral solution |
17 |
Sodium benzoate, saccharin sodium |
22 |
Fusidic acid, ophthalmic solution |
16 |
Benzalkonium chloride, disodium edetate |
23 |
Morphine, inj solution |
14 |
Sodium metabisulphite |
24 |
Phenobarbital, inj solution |
13 |
Benzyl alcohol, propylene glycol |
25 |
Heparin sodium, topical gel |
12 |
Parabens, ethanol, trietanolamine, |
26 | Insulin, inj solution | 11 | Cresol |
Inj - injection.