Table 1.
MicroRNA profiling of alpha-synuclein containing exosomes from H4 cell culture media
| miRNAs | function | remarks | Key citations |
|---|---|---|---|
| 7b |
Inhibition of cell cycle progression and growth of melanoma cells |
present in exosomes |
[38,39] |
| 7i |
regulatory responses to microbial infection |
present in exosomes |
[40,41] |
| 18b |
exocytosis, angiogenesis, hematopoiesis, tumorgenesis |
present in exosomes |
[40] |
| 182 |
Repression of tumor suppressors |
present in exosomes |
[39,42] |
| 184 |
Block of NFAT1 protein expression |
present in exosomes |
[40,43] |
| 363* |
- |
|
[44,45] |
| 373* |
Involvement in tumor migration and invasion |
present in exosomes |
[39,46] |
| 375 |
exocytosis, angiogenesis, hematopoiesis, tumorgenesis |
present in exosomes |
[39,40] |
| 376* |
- |
|
[47,48] |
| 424 |
controlling the macrophage differentiation program |
present in exosomes |
[39,49] |
| 431 |
- |
CNS specific miRNA |
[47,50] |
| 455 |
- |
|
[51] |
| 487a |
Role in angiogenesis and cell aging |
|
[52] |
| 492 |
- |
|
[44] |
| 494 |
regulation of PTEN expression and functions as a micro-oncogene in carcinogenesis |
present in exosomes |
[39,53] |
| 518c | - | [44,54] |