. 2012 Oct 29;7(10):e48028. doi: 10.1371/journal.pone.0048028

Table 2. Cardiac and non-cardiac gene processes activated by Tbx5, Gata4, and Myocd.

Gene ontology name	T	G	M	T+G	G+M	T+M	T+G+M
Cardiac	(permute P value)
Wnt receptor signaling pathway	0.004^*	N	N	0.63	1.0	0.602	0.802
Circulation	0.54	0.016^*	0^*	0.01^*	0.015^*	0^*	0^*
Contractile fiber	N	N	0.01^*	N	N	0.001^*	0.002^*
Muscle contraction	N	N	0.002^*	0.767	0.126	0^*	0.006^*
Muscle development	0.213	0.803	0.016^*	1.0	0.469	0.077	0.032^*
Myofibril	N	N	0.005^*	N	N	0^*	0.006^*
Sarcomere	N	N	0.002^*	N	N	0^*	0.003^*
Structural constituent of cytoskeleton	N	N	0.043^*	N	0.518	0.131	0.013^*
Muscle cell differentiation	N	N	0.019^*	0.089	0.036^*	0.007^*	0.041^*
Striated muscle contraction	N	N	N	N	N	0^*	0^*
Regulation of heart contraction	N	N	N	N	N	N	0^*
Structural constituent of muscle	N	N	N	N	N	N	0.003^*
Glucose metabolism	N	0.115	0.586	0.083	0.428	0.417	0.009^*
Fatty acid oxidation	N	0.001^*	N	0^*	0.02^*	0.039^*	0.046^*

GO terms with permute p<0.05 and a nested gene change number ≥4 were considered to be significantly activated. GOs with a nested gene change number <4 were shown as “N”. GO terms that were both activated and inhibited were excluded. T, Tbx5; G, Gata4; M, Myocd.