Table 1. Blood and Plasma measurements from WNIN/GR-Ob Rats.

Parameter	Mutant	Lean	Control
Blood Glucose (mg/dl)	91.0±2.83*	74.5±4.95	77.5±2.12
Plasma Insulin (µU/ml)	21.76±5.76*	7.24±2.05	3.63±2.45
Indices of Insulin Resistance (IR)
FGIR	1.12±0.02*	0.73±0.01*	8.03±0.08
QUICKI	0.01±0.0*	0.02±0.0	0.04±0.01
HOMA-IR	1.60±0.04*	1.38±0.02*	0.20±0.01

The Mutant rats demonstrated hyperinsulinemia which was significant compared to their Lean and Control. An increase in blood glucose levels was also evident among Mutants. IR was calculated based on three functions - a) FGIR <4.5 mg/10⁻⁴U; b) QUICKI – Lower among Obese; c) HOMA-IR >1 Asteric (*) indicates significance at p<0.05 by ANOVA compared to control. Values are represented as Mean ± SE (n = 6) from six animals per group.

Abbreviations:

FGIR: Fasting Glucose to Insulin Ratio, QUICKI: Quantitative Insulin Sensitivity Check Index, HOMA-IR: Homeostasis Model of Assessment for Insulin Resistance.