Table 2.

Selected^* phenotypic and genotypic assessments of Framingham Heart Study participants for integration with data from the ECG Repository.

Assessment	Participating Cohorts and Exams
Echocardiography – cardiac structure and function	Original – 20
	Offspring – 4, 5, 6
	Third Generation – 1
Computed tomography, cardiac and chest	Offspring – 7
	Third Generation – 1
Pulmonary function testing	Offspring – 3, 5, 6, 7, 8
	Third Generation – 1
Biomarkers (BNP, CRP, IL-6, IL-18)	Offspring – 2, 6, 7
	Third Generation – 1
Cardiac and non-cardiac outcomes (Cardiovascular disease, atrial fibrillation, revascularization procedures)	Through 2010
Arterial tonometry	Original – 26
	Offspring – 7
	Third Generation – 1
Genetic sequencing	All participants
Genomics, metabolomics, proteomics	Offspring – 6
	Third Generation – 1

^*Selected as representative assessments from the comprehensive Framingham Heart Study evaluations described at www.framingham.org. Of note, all participants did not undergo the studies described. All examinations include standardized physical exam, anthropometry, interview, clinical history, medication inventory, and laboratory studies.

^**Original, Original Cohort; Offspring, Offspring Cohort;