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H2S contributes to carotid body chemosensory response to acute hypoxia. Representative in situ carotid sinus nerve recordings from one sham rat (upper panel) and one CHF rat (lower panel) before and after inhibition of H2S synthesis. Acute PAG treatment (100 mg/kg i.p.) reduced the carotid body chemosensory response to hypoxia (FiO2 10%) in both sham and CHF rats.
