TABLE 2.
HR and 95% CI of fracture by baseline osteocalcin: HR per value greater than the median (15.1 ng/mL)
| HR | 95% CI | P | |
|---|---|---|---|
| Unadjusted | 1.33 | 0.99–1.97 | 0.060 |
| Adjustments | |||
| Model 1: age | 1.49 | 0.99–2.53 | 0.057 |
| Model 2: +race and site | 1.42 | 0.94–2.45 | 0.102 |
| Model 3: +fracture history | 1.11 | 0.84–1.60 | 0.52 |
| Model 4: +lumbar spine BMD | 0.98 | 0.75–1.41 | 0.92 |
| Model 5: +height and weight | 1.04 | 0.78–1.52 | 0.81 |
| Model 6: +menopause status at baseline | 1.06 | 0.79–1.56 | 0.72 |
| Full multivariate modela | 1.11 | 0.85–1.67 | 0.53 |
Each consecutive model includes variables in the previous model. Time of collection was adjusted for in each model.
HR, hazard ratio; BMD, bone mineral density.
a
Full multivariate model covariates included time of collection, baseline age, race, site, fracture history, lumbar spine BMD, height, weight, menopause status, education, alcohol use, smoking, and diabetes.