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. 2012 Nov;22(11):2176–2187. doi: 10.1101/gr.136788.111

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© 2012, Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genome.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 4. — Aligned dCTCF sites are enriched at the borders of H3K27me3 and physical domains. (A) Percentage of independent and aligned dCTCF sites within 5 kb from recently mapped physical domain boundaries (Sexton et al. 2012). (B) Average read intensity for insulator proteins at physical domain boundaries, ±10 kb. Comparison of insulator profiles normalized by total read numbers. (C) Percentage of independent and aligned dCTCF sites within 5 kb from H3K27me3 domain borders. (D) Average read intensity for H3K27me3 and insulator proteins at H3K27me3 domain borders, ±2 kb. Comparison of insulator profiles normalized by total read numbers.