Table 1.
TOMM40S/S | TOMM40 S/L | TOMM40 S/VL | TOMM40 L/L | TOMM40 L/VL | TOMM40 VL/VL | p | |
---|---|---|---|---|---|---|---|
N | 88 | 107 | 193 | 54 | 87 | 110 | |
Mean Entry Age (standard deviation) | 57.8 (13.6) | 57.3 (12.9) | 59.3 (12.9) | 56.1 (9.9) | 55.3 (12.1) | 60.9 (11.2) | 0.02 |
Mean Years Education (standard deviation) | 15.6 (2.3) | 15.7 (2.5) | 15.6 (2.5) | 15.8 (2.3) | 15.5 (2.6) | 15.6 (2.7) | 0.99 |
#Female (%) | 67 (76.1) | 72 (67.3) | 127 (65.8) | 42 (77.8) | 65 (74.7) | 72 (65.5) | 0.22* |
% FDR | 52.9 | 69.8 | 47.6 | 81.1 | 79.1 | 57.3 | <0.001* |
%Caucasian | 100 | 100 | 98.1 | 100 | 100 | 100 | 0.68* |
% >1 epoch | 81.8 | 84.1 | 78.8 | 85.2 | 78.2 | 82.7 | 0.76* |
FDR=first degree relative with dementia. Unpaired t-tests except (*) chi square.