Skip to main content
. 2012 Oct 30;4(6):e00100. doi: 10.1042/AN20120062

Figure 5. CSPGs are increased in the corpus callosum after cuprizone treatment.

Figure 5

Immunohistochemistry of coronal sections through the CC (corpus callosum) immunostained for a pan-CSPG moiety with CS-56 antibody (red). CS-56 immunoreactivity is relatively low in the normal adult CC (A, 26 weeks) but increases with 6 (B) or 12 (D) weeks of cuprizone treatment. After the 6-week recovery period on normal chow, CS-56 immunoreactivity was more prominent after 12 weeks of cuprizone (E) than after only 6 weeks of cuprizone (C). Nuclei are stained with DAPI (4′,6-diamidino-2-phenylindole; blue). Scale bar for (A–C) shown in (A) = 100 μm. Scale bar for (D, E) shown in (D) = 200 μm.