Table 3.

Within-group activation data for both premutation carriers and control group on the whole-brain level for the encoding > scrambled trials.

Group	Area of activation	Cluster size	Z max	Peak coordinates
Controls	B angular gyrus	14078	7.52	26 −46 −12
	B cerebellum
	B fusiform gyrus
	B hippocampus
	B lingual gyrus
	B mid. and inf. occipital lobe
	B parahippocampal gyrus
	B precuneus
	R mid. and B inf. temporal gyrus
	Orbital frontal cortex	366	5.06	−8 42 −16
	L dorsolateral prefrontal cortex	282	4.29	−42 8 32
		54	3.8	54 −8 −22
	Posterior cingulum	265	5.68	0 −38 40
	L ventrolateral prefrontal cortex	102	5.36	−30 30 −22
	R precentral gyrus	86	4.21	24 −24 56
		30	0.001	64 −2 12
		42	0.001	56 0 24
	R dorsolateral prefrontal cortex	80	4.14	30 32 −14
	L postcentral gyrus	64	4.21	−54 −8 26
	L mid. and inf. temporal gyrus	43	3.97	−58 −8 −24
Premutation carriers	L cerebellum	4747	7.26	−32 −36 −22
	L fusiform gyrus
	L hippocampus
	L lingual gyrus
	L mid. and inf. occipital lobe
	L parahippocampal gyrus
	L precuneus
	R calcarine gyrus	4530	7.03	28 −46 −12
	R fusiform gyrus
	R hippocampus
	R lingual gyrus
	R mid. and inf. occipital lobe
	R mid. and inf. temporal gyrus
	R parahippocampal gyrus
	R precuneus
	R ventrolateral prefrontal cortex	65	4.75	32 34 −16
	L ventrolateral prefrontal cortex	55	5.04	−32 32 −18

The thresholding is set at p < 0.01 with FDR correction and number of voxels in a cluster >25.