Table 5.
Between-group comparisons of encoding task dependent functional coupling (PPI) with the hippocampi as seeded regions.
Seeded region | Coupled region | Controls | Premutation carriers | Significance |
---|---|---|---|---|
Left hippocampus | L BA 47 (VLPFC) | 0.0120 | −0.2423 | p = 0.037 |
Right hippocampus | R BA 47 (VLPFC)* | 0.0419 | −0.2353 | p = 0.016 |
R BA 46 (DLPFC) | 0.1571 | −0.1100 | p = 0.028 | |
R parahippocampal gyrus* | 0.2438 | −0.0950 | p < 0.001 |
Average intensity levels shown were extracted for each participant using individually non-normalized, individually traced hippocampal masks using Marsbars toolbox (Brett et al., 2002).
*Denotes significant between-group co-activation differences when corrected for multiple comparisons