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. Author manuscript; available in PMC: 2013 Sep 20.
Published in final edited form as: Neuron. 2012 Sep 20;75(6):1035–1050. doi: 10.1016/j.neuron.2012.08.031

Figure 1. Radial glial properties are not maintained in the absence of Mek1/2.

Figure 1

(A–B′) The expression of radial progenitor markers, RC2 and GLAST, is strongly reduced in E17.5 Mek1,2\Nes mutant radial progenitors (n=3). In A–A′, scale bar=100μm. In B–B′, scale bar=50 μm. (C–C′) Pax6 immunostaining of radial progenitor nuclei is not obviously different between E17.5 Mek1,2\Nes and WT cortices. Scale bar=100 μm. (D–D′) EGFP labeled radial progenitors at E18 after in utero electroporation of pCAG-EGFP into E16.5 Mek1,2\Nes and WT dorsal cortices. Radial progenitors in Mek1,2\Nes animals exhibited a normal morphological appearance. See also Figure S1.