Table 2.
Immune Cell Composition in Mtb CDC1551-Infected Rabbit Lungs
| Time p.i. (weeks) | Nonlymphocyte mononuclear cells⁎ | Lymphocytes⁎ | CD4+† | CD8+† | B cells† | Serum IgG‡ |
|---|---|---|---|---|---|---|
| 4 | 32.8 ± 4.6 | 66.7 ± 4.7 | 3.4 ± 0.5 | 3.9 ± 2.0 | 79.3 ± 6.3 | 2.0 ± 0.8 |
| 8 | 72.2 ± 2.9 | 27.3 ± 3.0 | 19.1 ± 1.5 | 6.1 ± 0.6 | 73.7 ± 4.0 | 3.2 ± 0.8 |
| 12 | 64.1 ± 7.4 | 35.7 ± 7.4 | 3.4 ± 0.6 | 2.0 ± 0.5 | 86.1 ± 2.4 | 3.0 ± 0.6 |
Data are given as mean ± SD. The percentages of cells in single-cell suspensions were identified by immunostaining and flow cytometry.
⁎
Data are given as percentage of total mononuclear cell population.
†
Data are given as percentage of total lymphocyte gated cell population.
‡
IgG levels are expressed as ng/μL on a log10 scale. The IgG value at baseline (3 hours after infection) was 2.0 ± 0.2.