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SCD mice have elevated serum IL-6 and decreased IL-1a cytokine expression. A and B: C57BL/6 (n = 11), hemizygous (Hemi; n = 11), and SCD (n = 9) mice undergo serum cytokine analysis via Luminex bead assay. Bars represent mean ± SEM levels. Significant differences are determined by one-way analysis of variance with multiple pairwise comparisons between groups using the Newman-Keuls post hoc test. *P < 0.05, **P < 0.01, and ***P < 0.001.
