Table 3.
Author | Total number of LA | Total number of malignant cases | Mean tumor size (cm) | Duration of followup (months) | Recurrence rate | Comments |
---|---|---|---|---|---|---|
Henry et al., 2002 [24] | 233 | 6 ACC | 7.4 | 47 | 17% | 1 dead of disease |
Porpiglia et al., 2004 [25] | 205 | 6 ACC | 6.9 | 30 | 0% | 1 dead of cerebrovascular accident |
Corcione et al., 2005 [26] | 100 | 2 ACC | 8.5 | 13.6 | 50% | Both patients alive, one has still disease |
Gonzalez et al., 2005 [19] | 6 | 6 ACC | 5.3 | 28 | 100% | 2 are still alive with disease, remaining 4 died of disease |
Palazzo et al., 2006 [27] | 391 | 3 MP | 6.8 | 34 | 33% | 1 dead of disease |
Lombardi et al., 2006 [28] | 79 | 4 ACC 3 MP |
5.9 | 23 | 29% | 4 alive disease free, 2 alive with disease and one dead of liver failure |
Liao et al., 2006 [29] | 210 | 4 ACC | 6.2 | 39 | 25% | 1 alive disease free, 1 alive with disease and 2 died of disease |
Nocca et al., 2007 [30] | 131 | 4 ACC | 8.5 | 34 | 25% | 3 alive disease free, 1 died of metastatic disease |
Ramacciato et al., 2008 [31] | 18 | 2 ACC | 8.3 | 44 | 0% | Alive and disease free |
Brix et al., 2010 [32] | 35 | 35 ACC | 6.2 | 39 | 77% | 37% of patients died from ACC |
Miller et al., 2010 [33] | 17 | 17 | 7.0 | 36 | 20% | Not investigated, but authors concluded that the mean time to local recurrence was shorter in LA compared to the open group |
ACC: adrenocortical cancer; MP: malignant pheochromocytoma; LA: laparoscopic adrenalectomy.