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. 2012 Feb;102(2):309–318. doi: 10.2105/AJPH.2011.300343

TABLE 4—

Summary of Individual Participant Data Odds Ratio Modification Analyses for Algorithmic Translation of Mechanical Exposure of Study-Level Variables in Studies of Mechanical Workplace Risk Factors and Low Back Pain

LBP in the Past 6 Months to 2 Years
Current LBP
Sick Leave Attributable to LBP
Variables Posture 1A Posture 1B Posture 1C Posture 2A Posture 2B Posture 2Ca Force 1Ca Force 2C Posture 2A Posture 2B Posture 2Cab Posture 2Aab Posture 2B Posture 2C Force 1C Force 2C
Studies, no.c 4 3 7 5 5 14 14 11 2 4 8 3 5 7 7 7
Study design, OR
 Cross-sectional 1.13 1.90d 1.65d 2.09 1.19
 Cohort 1.25 1.44d 1.27d 0.96 2.74
Study design,e OR
 Cross-sectional 1.27 1.90d 1.65d 2.09 1.19
 Cohort 1.14 1.33d 1.17d 0.69 2.76
Participation rate > 80%,OR
 Not reported 1.43d 1.18 1.15 2.74
 Reported 1.89d 1.49 2.08 1.19
Exposure reliability, OR
 Not reported 1.13 1.30 1.57d 1.66 3.20 2.42
 Reported 1.25 1.94 1.10d 2.77 1.13 1.94
Outcome reliability, OR
 Not reported 0.99 3.20 1.95
 Reported 1.57 1.13 2.15
Dose–response analysis,OR
 Not reported 2.25
 Reported 1.80
Exposure type, OR
 Observation-based 0.98 1.01d 1.07d 0.96 1.80
 Self-report 1.50 1.82d 1.59d 2.09 2.25
Population type, OR
 Workplace-based 1.30 1.43d 1.24d 1.26
 Population-based 1.63 1.94d 1.70d 2.14

Note. LBP = low back pain; OR = odds ratio. Posture 1 = trunk flexion; posture 2 = nonneutral posture; force 1 = lifting; force 2 = heavy lifting; “A” exposures represent the percentage of a workday spent in a nonneutral posture or exerting a force; “B” exposures represent the percentage of job tasks requiring a nonneutral posture or exerting a force; “C” exposures represent ever experiencing a nonneutral posture or exerting a force.

a

The outcome–exposure combinations with heterogeneity indicated in aggregate data analysis.

b

Meta-regression not done because the number of studies was < 10.

c

Analyses include all studies of the variable of interest. The total number of studies included in each analysis may vary.

d

Variable also identified as an odds ratio modifier in meta-regression.

e

Includes only incident cases for cohort studies.