Table 1.
Characteristics of children at the time of enrollment (N=2649)
|
Characteristic |
Year of surveillance |
P |
|||
|---|---|---|---|---|---|
| 2005 | 2006 | 2007 | 2009 | ||
| Time-period of enrollment |
February 28 to June 7 |
February 2 to April 13 |
February 26 to May 17 |
February 24 to May 19 |
|
| PCV7 in the National Immunization Program |
-- |
+ |
+ |
+ |
|
| PCV7 reimbursed |
-- |
-- |
+ |
+ |
|
| No. of enrolled children |
769 |
494 |
566 |
820 |
|
| Age, median (range), months |
49 (15–76) |
46.5 (13–70) |
46 (13–73) |
48 (14–72) |
— |
| Male gender |
417 (54.2)a |
248 (50.2) |
297 (52.5) |
427 (52.1) |
0.529 |
| Antibiotic use in the preceding 3 months |
433/764b (56.7) |
260/489 (53.2) |
284/566 (50.2) |
459/818 (56.1) |
0.647 |
| Vaccinated with ≥1 dose of PCV7 |
99 (12.9) |
161 (32.6) |
397 (70.1) |
783 (95.5) |
<0.001 |
| Age-appropriately vaccinated |
92 (12) |
150 (30.4) |
351 (62) |
668 (81.5) |
<0.001 |
|
Streptococcus pneumoniae carriage |
|
|
|
|
|
| per age-group, months |
|
|
|
|
|
| 13 − 23 |
12/21 (57.1) |
11/22 (50) |
18/26 (69.2) |
13/18 (72.2) |
0.176 |
| 24 – 35 |
74/121 (61.2) |
34/69 (49.3) |
50/99 (50.5) |
43/100 (43) |
0.01 |
| 36 – 47 |
130/231 (56.3) |
78/185 (42.2) |
84/183 (45.9) |
118/279 (42.3) |
0.006 |
| 48 – 59 |
101/240 (42.1) |
70/188 (37.2) |
109/208 (52.4) |
132/349 (37.8) |
0.721 |
| ≥60 |
53/156 (34) |
13/30 (43.3) |
25/50 (50) |
28/74 (37.8) |
0.273 |
| Overall | 370 (48.1) | 206 (41.7) | 286 (50.5) | 334 (40.7) | 0.036 |
aNumber in parentheses is percent, unless otherwise indicated.
bThe denominator indicates the number of children with available information on recent antibiotic use.