Table 1.
Clinical, treatment, ELISA and MRI information for 18 children with cerebral sparganosis
Case | Age/sex | Ingestion of pathways | Presenting symptom(s) |
Results of ELISA |
Treatment | MRI follow-up period (m) | MRI enhancement Patterns | |
---|---|---|---|---|---|---|---|---|
Serum | CSF | |||||||
1 |
6/F |
Frog (2y ago) |
Headache, altered mental status |
+ |
+ |
Praziquantel |
NF |
tortuous linear shaped enhancement |
2 |
3/M |
NI |
Seizures |
+ |
+ |
Degenerated worm removed |
NF |
serpiginous tubular enhancement |
3 |
5/M |
NI |
Hemiparesis, dizziness |
+ |
+ |
Praziquantel |
2 |
beaded enhancement |
4 |
11/M |
NI |
Headache, seizures |
+ |
+ |
Praziquantel |
NF |
ring enhancement |
5 |
14/F |
Frog (6y ago) |
Altered mental status |
+ |
+ |
Praziquantel |
6 |
tortuous linear shaped enhanceme |
6 |
4/F |
Untreated water (for 1y) |
Hemiparesis |
+ |
+ |
Removal of live worm |
NF |
ring enhancement |
7 |
7/M |
NI |
Headache, blurred vision, palsy |
+ |
+ |
Praziquantel |
1 |
beaded enhancement |
8 |
13/M |
uncooked crabs (8y ago) |
Seizures, altered mental status |
+ |
+ |
Praziquantel |
5 |
beaded enhancement |
9 |
15/M |
NI |
Headache, projectile vomiting |
+ |
+ |
Degenerated worm removed |
NF |
ring enhancement |
10 |
9/F |
NI |
Hemiparesis |
+ |
+ |
Praziquantel |
7 |
comma shaped and ring enhancement |
11 |
12/M |
uncooked crabs (6y ago) |
Seizures, hemiparesis |
+ |
+ |
Praziquantel |
NF |
beaded enhancement |
12 |
9/F |
NI |
Headache, intermittent seizures |
+ |
+ |
Live worm removed |
7 |
serpiginous tubular enhancement |
13 |
9/M |
NI |
Headache, seizures, blurred vision |
+ |
+ |
Praziquantel |
5 |
nodular enhancement |
14 |
10/M |
NI |
Headache, altered mental status |
+ |
+ |
Praziquantel |
NF |
beaded enhancement |
15 |
7/F |
NI |
Seizures |
+ |
+ |
Praziquantel |
3 |
beaded enhancement |
16 |
5/M |
NI |
Seizures, dizziness |
+ |
+ |
Praziquantel |
NF |
serpiginous tubular enhancement |
17 |
6/F |
NI |
Altered mental status |
+ |
+ |
Praziquantel |
7 |
nodular enhancement |
18 | 17/F | Untreated water (for 5y) | Seizures | + | + | Praziquantel | NF | beaded enhancement |
Note:NI = no ingestion; + = positive; - = negative; NF = no follow-up.