Table 5.
Description of adverse events that are likely related to antiretroviral therapy
| Adverse events | Severity (grade) | Resources consumed for the management of the adverse event |
|---|---|---|
|
Non-exposed group (n = 150) |
|
|
| 1. Dizziness after an error in taking AtriplaTM |
1 |
- |
| 2. Neuropsychiatric: insomnia, anxiety, and abnormal dreams* |
1 |
- |
|
Exposed group (n = 75) |
|
|
| 1. Neuropsychiatric: dizziness |
2 |
- |
| 2. Neuropsychiatric: insomnia, abnormal dreams* |
2 |
- |
| 3. Neuropsychiatric: depression, insomnia* |
1 |
- |
| 4. Neuropsychiatric: insomnia |
2 |
Infectious disease consult |
| 5. Diarrhoea |
2 |
- |
| 6. Vomiting |
2 |
- |
| 7. Hepatic toxicity |
4 |
Specialist and nursing consults, hospital admissions, chest x-rays, abdominal ultrasound, and hepatic biopsy |
| 8. Neuropsychiatric: dizziness, insomnia, and abnormal dreams* |
2 |
- |
| 9. Neuropsychiatric: insomnia, anxiety, loss of concentration, abnormal dreams, and HIV encephalopathy after stopping treatment* |
4 |
Infectious disease consults, hospital admissions, cranial CAT scan, cerebral MRI, and lumbar puncture |
| 10. Neuropsychiatric: dizziness |
1 |
- |
| 11. Psychiatric: depression, insomnia, anxiety, abnormal dreams, and hallucinations* |
3 |
Emergency department admission, mental health consult |
| 12. Hepatic toxicity |
3 |
Infectious disease consult, nursing, biochemistry, serology, and abdominal ultrasound |
| 13. Neuropsychiatric: dizziness, insomnia, headache, and abnormal dreams* |
2 |
Infectious disease consult |
| 14. Diarrhoea | 2 | - |
*Patients with more than one type of neuropsychiatric adverse event. The grade of the more severe AE is specified.