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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Prog Biophys Mol Biol. 2012 Jul 24;110(2-3):295–304. doi: 10.1016/j.pbiomolbio.2012.07.005

Figure 3. Propagation characteristics of an intercellular calcium wave.

Figure 3

A calcium wave propagating through 10 cells (500 sarcomeres) is initiated by opening RyRs at one end of the first cell. Bottom panel: The corresponding transmembrane potential is almost constant; relative changes corresponding to the movement of the calcium wave are in the range of about 0.8%. Time is in ms, and space is node number; xj = jΔx, j = 1, . . . , 50, where Δx = 2 μm is the length of a sarcomere, concentration of [Ca]i (upper panel) is in μM, and transmembrane potential (lower panel) is in mV. The speed of the wave starts at about 100 μm/s and slows down gradually as the wave decays to the resting state.