Table I.
1. Saline Injected TA + Saline Injected PCA: “Saline” (Ctl) Group (n=12) | 2 months (n=6) |
4 months (n=6) | |
2. MSC Injected TA + Saline Injected PCA: “EGFP” Group (n=12) | 2 months (n=6) |
4 months (n=6) | |
3. NF-MSC Injected TA + Saline Injected PCA: “CNTF” Group (n=12) | 2 months (n=6) |
4 months (n=6) | |
3. MSC Injected TA+ VNC Injected PCA: “EGFP-VNC” Group (n=12) | 2 months (n=6) |
4 months (n=6) | |
4. NF-MSC Injected TA+ VNC Injected PCA: “CNTF-VNC” Group (n=12) | 2 months (n=6) |
4 months (n=6) |
TA: thyroarytenoid muscle complex; PCA: posterior cricoarytenoid muscle; MSC: control muscle stem cells with tracking marker EGFP (enhanced green fluorescent protein); NF-MSC: neurotrophic factor-secreting muscle stem cells; Ctl: control. All animals undergo left RLN transection injury 3 weeks prior to the therapeutic injections. Follow-up time periods (right) are relative to the time of RLN Injury.