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Cellular uptake of siRNA in vitro. (a) Fluorescence photographs of cultured A549 cells after treatment with 5′-FAM-labeled oligo in non-targeted or targeted LCP for 4 h. (b) Quantitative measurement of mean fluorescence intensity of cell lysate from A549 cells treated with 5′-FAM-labeled oligo formulated in non-targeted or targeted LCP. A549 cells were incubated at 37 °C for 4 h in the absence or presence of 50 μM haloperidol. Columns, mean (n = 3); bars, SD. *, p < 0.05.
