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Serum levels of ALT, AST and BUN after long-term treatment with therapeutic siRNA in the targeted LCP
| ALT (U/L) | AST (U/L) | BUN (mg/dL) | |
|---|---|---|---|
| Untreated group | 55.5 ± 9.12 | 140.5 ± 10.61 | 16 ± 2.83 |
| Therapeutic siRNA in targeted LCP treated group | 58.33 ±17.5 | 149.33 ± 24.91 | 20 ± 5.29 |
Measurements were carried out with the aim of evaluating the potential long-term toxicity of pooled siRNA in the targeted LCP. Data = mean ± SD (n = 5).
