Tumor volumes before and at different time points after the course of treatment (n = 10 mice). Mice were treated with 4 doses of 17-DMAG 24 h apart. With the first dose of treatment, tumor volume started to reduce, but after the course of treatment, the tumor started to regrow to its original volume. To monitor the variations in the HER2 overexpression specific marker, Affibody-Alexa Fluor 750 conjugate was injected through the tail vein before, and 12 h and 7 d after the course of treatment.