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. Author manuscript; available in PMC: 2013 Sep 28.
Published in final edited form as: Oncogene. 2012 May 21;32(13):1616–1625. doi: 10.1038/onc.2012.193

Figure 1.

Figure 1

HOTAIR expression and prognostic significance in pancreatic cancer. (A) HOTAIR expression in normal pancreas and pancreatic tumors from patients (24) and Kaplan-Meier plot for survival of pancreatic cancer patients expressing high and low HOTAIR (25). (B) Relative expression of HOTAIR in pancreatic cancer patients with tumor localized in the pancreas (NO) or those with tumors already spread to regional lymph nodes (NO) or patients with tumor detected only in the pancreas (T2) and tumors extending beyond the pancreas (T3) (24). (C) GSEA analysis of GO terms showed that there was enriched expression of gene sets involved in cell cycle progression in pancreatic cancer patients. (D) Expression of HOTAIR in pancreatic cancer cells as determined by real time PCR or from array data (26).