Table 4.
Clinico-pathological characteristics of esophageal squamous cell carcinoma patients investigated from Lublin region
| Characteristic |
HPV positive |
HPV high risk |
HPV low risk |
|||
| n (%) | P value | n (%) | P value | n (%) | P value | |
| Gender | ||||||
| Male | 23 (46.9) | 0.44351 | 2 (4.1) | 0.02941 | 17 (34.7) | 0.12541 |
| Female | 5 (71.4) | 3 (42.9) | 2 (28.6) | |||
| Age (yr) | ||||||
| > 50 | 25 (54.4) | 0.72741 | 3 (6.5) | 0.23321 | 18 (39.1) | 0.22171 |
| < 50 | 3 (30.0) | 2 (20.0) | 1 (10.0) | |||
| Macroscopic type | ||||||
| ULC | 2 (20.0) | 0.02932 | 0 (0.0) | 0.11252 | 2 (20.0) | 0.14482 |
| INF | 5 (83.3) | 1 (16.7) | 4 (66.7) | |||
| ULC/INF | 15 (71.4) | 3 (14.3) | 9 (42.9) | |||
| PROT | 6 (31.6) | 1 (5.3) | 4 (21.1) | |||
| Grading | ||||||
| G1 | 3 (75.0) | 0.32342 | 1 (25.0) | 0.26382 | 2 (50.0) | 0.29112 |
| G2 | 19 (44.2) | 3 (7.0) | 15 (34.9) | |||
| G3 | 6 (66.7) | 1 (11.1) | 2 (22.2) | |||
| Staging | ||||||
| II | 11 (36.7) | 0.27202 | 3 (10.0) | 0.61062 | 6 (20.0) | 0.35372 |
| III | 14 (73.7) | 2 (10.5) | 10 (52.6) | |||
| IV | 3 (42.9) | 0 (0.0) | 3 (42.9) | |||
| Tumor | ||||||
| T2 | 11 (57.9) | 0.34582 | 3 (15.8) | 0.10132 | 7 (36.8) | 0.31252 |
| T3 | 15 (51.7) | 1 (3.5) | 11 (37.9) | |||
| T4 | 2 (25.0) | 1 (12.5) | 1 (12.5) | |||
| Nodes | ||||||
| N0 | 12 (48.0) | 0.76041 | 3 (12.0) | 0.24841 | 7 (28.0) | 0.46261 |
| N1 | 16 (51.6) | 2 (6.5) | 12 (38.7) | |||
1
Mann-Whithey U test;
2
Kruskal-Wallis test. HPV: Human papilloma virus; ULC: Ulcerative; INF: Infiltrative; PROT: Protruding.