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Non-muscle myosin II inhibition increased airway branching and peripheral airway size. (A). Low power time-lapse images of control and blebbistatin treated explants. Dilated peripheral airways clearly visible by 18 h. (B) Blebbistatin increased peripheral airway size by 18 h (* P < 0.05, n = 5). (C, D) Blebbistatin increased airway branch formation following 4 h of treatment, but had no effect between 4 h and 18 h (* P < 0.05, n = 5).
