Table 2.
Biodistributions of 68Ga-DOTA-DG, 18F-FDG, and 68Ga-DOTA in mice bearing A431 tumors at 1 hour after radiotracer injection
| Mean %ID/g (± standard deviation) | |||
|---|---|---|---|
|
|
|||
| Site | 68Ga-DOTA | 68Ga-DOTA-DG | 18F-FDG |
| Blood | 0.44±0.07 | 0.40±0.09 | 0.54±0.10 |
| Heart | 0.11±0.02 | 0.12±0.03 | 30.2±7.40 |
| Liver | 11.96±0.90 | 0.36±0.01 | 0.69±0.21 |
| Spleen | 2.77±1.13 | 0.21±0.02 | 1.50±0.60 |
| Kidney | 0.72±0.04 | 1.19±0.11 | 1.07±0.06 |
| Lung | 0.39±0.02 | 0.26±0.06 | 2.30±0.64 |
| Stomach | 0.11±0.05 | 0.12±0.01 | 2.93±1.50 |
| Intestine | 0.06±0.02 | 0.16±0.05 | 1.42±0.40 |
| Muscle | 0.03±0.00 | 0.12±0.13 | 2.37±0.16 |
| Bone | 0.07±0.01 | 0.07±0.03 | 2.06±0.44 |
| Tumor | 0.20±0.07 | 0.39±0.04 | 4.26±1.10 |
| Brain | 0.03±0.00 | 0.03±0.02 | 5.81±2.83 |
| Tumor/muscle | 7.82±2.40 | 6.75±5.55 | 1.80±0.47 |
| Tumor/brain | 7.83±2.56 | 14.03±2.00 | 0.79±0.18 |
| Tumor/heart | 1.75±0.33 | 3.30±0.71 | 0.15±0.04 |
| Tumor/liver | 0.02±0.00 | 1.08±0.11 | 6.40±1.62 |
| Tumor/kidney | 0.27±0.08 | 0.33±0.05 | 3.96±0.92 |