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. 2012 Oct 24;122(11):4172–4189. doi: 10.1172/JCI63377

Figure 8. Heterotopic expression of wtOCN improves glucocorticoid-induced insulin resistance.

Figure 8

ITTs in EV- (red) and wtOCN (black) vector–receiving mice (vector administered via hTVI on day 8) treated with either placebo (solid lines) or 1.5 mg corticosterone per week (dashed lines) on (A) day 0, (B) day 7, (C) day 14, (D) day 21, and (E) day 28. *P < 0.05, #P < 0.01, P < 0.001 compared with respective vector-receiving placebo-treated controls; P < 0.05 compared with other corticosterone-treated groups receiving μOCN or wtOCN vectors (repeated-measures ANOVA followed by post-hoc analysis for time-dependent measurements; error bars represent SEM).