Table 1.
Comparison of the efficacy of serum GP73 and AFP levels in the diagnosis of HCC
| References | AFP-negative (%) | GP73 | AFP | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| AUROC | Sensitivity | specificity | AUROC | Sensitivity | specificity | ||
| Marrero et al 2005 | 62% (32/52) | 0.79 | 69% | 86% | 0.61 | 30% | 96% |
| Mao et al 2008 | 35.1% (12/37) | — | 76.9% | 92.9% | — | 48.6% | 75% |
| Wang et al 2009 | — | 0.94 | 95 % | 70 % | 0.83 | 95% | 28% |
| Hu et al 2010 | 49.1% (61/124) | 0.89 | 77.4% | 83.9% | 0.77 | 48.4% | 96.8% |
GP73, Golgi protein-73; AFP, Alpha-fetoprotein; AUROC, area under the receiver operating curve.