Table 1.
Clinical findings in all 8 reported cases of metastatic bone marrow involvement by Merkel cell carcinoma
| Gender | Age | Time from presentation of MCC to bone marrow metastasis | Immuno-suppressive agent | Disease resulting in immunosuppression | Outcome | |
|---|---|---|---|---|---|---|
| Current case | M | 64 | 3 months | No therapy in past 7 months | Myeloma | Death 6 months from presentation |
| Nemoto [8] | F | 73 | 7 months | prednisolone, methotrexate | SLE/Sjögrens | Death 8 months from presentation |
| Lentz [6] | M | 55 | 3 weeks | prednisone | SLE | Death 8 months from presentation |
| Gooptu [10] | F | 68 | unknown | Prednisolone, azathioprine | Rheumatoid arthritis | Death 2 months after presentation |
| Morris [11] | M | 72 | 4 months | Cyclosporine, mycophenolate mofetil, prednisolone | Renal transplant | Death prior to chemotherapy |
| Tam [12] | M | 66 | 6 months | Agents not reported | Heart transplant | Death 6 months from presentation |
| Tam [12] | M | 55 | MCC recently diagnosed | none | n/a | Lost to follow-up 6 weeks after presentation |
| Smadja [13] | F | 33 | 4 months | n/a | n/a | Death 1 week after metastasis |