Table 1.

Diagnostic criteria of neurofibromatosis type 1/Recklinghausen’s disease*

Six or more café au lait macules (>0.5 cm in children or > 1.5 cm in adults).

Two or more cutaneous or subcutaneous neurofibromas or one plexiform neurofibroma.

Axillary or inguinal freckling.

Optic pathway glioma

Two or more Lisch nodules (iris hamartomas seen on slit lamp examination)

One first-degree relative with NF-1

Two or more Lisch nodules

Bony dysplasia (sphenoid wing dysplasia, bowing of long bone +/- pseudoarthrosis)

^*two or more criteria are needed for diagnosis (from ref. 1).