Figure 2.

Calibration of XHMM CNV Quality Parameters with 90 Schizophrenia Trio Samples

We calibrate the XHMM parameters by considering how the number of rare CNVs per child (left panel), putative de novo events (middle panel), and parent-to-child transmission rates (right panel) vary as a function of increasingly stringent quality filtering. Boxes denote the interquartile range over all 90 trios. Horizontal solid lines indicate the median, and whiskers extend to the most extreme data points at most 1.5× the interquartile range from the box.